Transfusion Transmissible Infections

By virtue of Department Order No. 393-E series of 2000, the Research Institute for Tropical Medicine was designated as the National Reference Laboratory for confirmatory testing of blood donors and units. Under Memorandum Circular No. 126, the Transfusion Transmissible Infections – National Reference Laboratory (TTI-NRL) is mandated to perform confirmatory testing of blood donors and units screened reactive for Hepatitis B Virus, Hepatitis C Virus, Human Immunodeficiency Virus 1&2, Syphilis and Malaria among blood banks and blood service facilities nationwide. It also provides quality assurance and identify areas for improvement on:

a. Technical Procedures (specificity validation and monitoring of accuracy; site visits)
b. Kit Performance (evaluation through monitoring of screening test results)
c. Provide an External Quality Assessment Scheme to Blood Service Facilities

TTI-NRL provides recommendations and strategies to ensure the safety of blood supply from transfusion transmissible infections and quality assurance as a whole. It trains Medical Technologists of blood banks and/or blood service facilities on testing transfusion transmissible infections and conducts researches to provide data and improve the quality of testing among blood service facilities.


To be the center of excellence in performing quality procedures, trainings, and researches for the elimination of risks associated with transfusion transmissible infections.


The TTI-NRL ensures the safety of the national blood supply through confirmation of reactive blood units, provision of quality assurance and technical trainings, evaluation of test kit performance and the conduct of researches for the standardization of blood screening of Blood Service Facilities in the Philippines.


    The TTI-NRL delivers a range of testing services for reference testing of screened reactive blood donors to HIV, Hepatitis B and C, Syphilis and Malaria and these services are offered to all blood screening facilities nationwide. Our testing services involve serological and molecular tests to give the most satisfactory and accurate diagnoses.
    We provide a range of training services as an approach to build and enhance quality in laboratory systems for blood service facilities. Our training programs are designed to promote self-sufficiency and sustainability that will aid in the development of technical and analytical skills of the participant and also to promote best practices in laboratory testing. We deliver specialized training in HIV and other TTI Proficiency Testing and Biosafety Practices for medical technologists in blood service facilities.

    Due to the RITM response with the COVID-19 pandemic, we have cancelled all face-to-face events including trainings. 

    2021 HIV and other TTI Proficiency Testing Training Workshop Schedule:

    Full Course
    a. 26 April to 01 May
    b. 14 June to 19 June
    c. 09 August to 14 August
    d. 11 October to 16 October

    Refresher Course 
    a. 05 April
    b. 08 October – this batch will be exclusive for proficient MTs with expired licenses or due for expiry this 2021. Those that do not qualify will not be accepted. Please ensure that you visit our page regularly for the 2022 schedule of activities. Register through the RITM Learning and Development System link below.

    2022 HIV and other TTI Proficiency Testing Training Workshop Schedule: To Be Announced          

    The workshop will be conducted online and for more information on the details and registration, please visit the
    RITM Learning and Development System.

    To achieve the highest level of accuracy and reliability, it is essential that best practices are observed in the laboratory through the following activities:

    External Quality Assessment Scheme (EQAS)
    The TTI Serology EQAS generates valuable information on the types and brands of assays used in the country. This can provide a better overview of blood service facilities carrying out serological tests of transfusion transmissible infections as well as their activities. With this, we can monitor the performance of laboratories and identify those which require training to improve their performance. Participating laboratory can learn from the results and can be reassured that their performance is up to standard or they will be made aware to correct problems that would otherwise have gone unnoticed. Strategies and recommendation are provided to strengthen the performance of each participating laboratory.

    The 2020 test event cycle for Transfusion Transmissible Infections was suspended along with the other programs offered by the Research Institute for Tropical Medicine due to the on-going response to the COVID-19 pandemic (please read DOH issuance 2020-0306).

    Relative to the licensing requirements, the 2021 test event cycle will resume and is scheduled as follows:

    Test Event 1
    (update as of 28 July 2021)
    Shipment Date: 04 August
    Test Event Deadline: 11 August

    Test Event 2
    Shipment Date: 22 September
    Test Event Deadline: 29 September

    Registration ended on 31 March 2021.

    For more information on the registration, please send us an email at

    Site Inspections
    With the EQAS results, monitoring of blood banks/blood service facilities are made to assess the quality, accuracy and reliability of laboratory testing results and the extent and nature of laboratory-related problems and errors. This covers every step in the procedure, from sample receipt through the final interpretation of the donor result.

    Provision of Quality Control Samples
    To assure that test runs are valid and reliable, external quality control samples should be used in the performance of each assay. These samples should be treated the same way as donor samples and are used to validate the test run.

    The interest of the TTI-NRL to perform researches as one of its mandates led the way in forming the Transfusion Transmissible Infections Study Group comprised of different infectious disease specialists of the Research Institute for Tropical Medicine.


Department of Health Issuances

Republic Acts

Manual of Standards

For inquiries, please contact us through the following:

Direct Line: +63 2 8808 2552
Trunkline: +63 2 8807 2628 local 229
Mobile: +63 998 459 5982 (Smart) | +63 916 639 3402 (Globe)
Viber: TTI-NRL PH Viber Community